Lura is indicated for the treatment of schizophrenia and depressive episodes associated with Bipolar disorder. It works through a combination of dopamine Type 2 (D2) and serotonin Type-2 (5HT2A) receptor antagonism, though its exact mechanism is unknown.
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Common effects include somnolence, akathisia, extrapyramidal symptoms, and nausea.
Avoid strong CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin) and inducers (e.g., rifampin, phenytoin).
Hypersensitivity to Lurasidone or its ingredients, and concurrent use with strong CYP3A4 inhibitors or inducers.
Category B. Lurasidone is excreted in human milk; consult your doctor to decide whether to discontinue nursing or the drug.
May increase mortality in elderly patients with dementia-related psychosis and suicidal thoughts in adolescents and young adults.
Store below 30°C in a dry place, protected from light.